45 research outputs found
High-Performance Silicon Nanowire Electronics
This thesis explores 10-nm wide Si nanowire (SiNW) field-effect transistors (FETs) for logic applications via the fabrication and testing of SiNW-based ring oscillators. Both SiNW surface treatments and dielectric annealing are reported for producing SiNW FETs that exhibit high performance in terms of large on/off-state current ratio (~108), low drain-induced barrier lowering (~30 mV), high carrier mobilities (~269 cm2/V•s), and low subthreshold swing (~80 mV/dec). The performance of inverter and ring-oscillator circuits fabricated from these nanowire FETs is explored as well. The inverter demonstrates the highest voltage gain (~148) reported for a SiNW-based NOT gate, and the ring oscillator exhibits near rail-to-rail oscillation centered at 13.4 MHz. The static and dynamic characteristics of these NW devices indicate that these SiNW-based FET circuits are excellent candidates for various high-performance nanoelectronic applications.
A set of novel charge-trap non-volatile memory devices based on high-performance SiNW FETs are well investigated. These memory devices integrate Fe2O3 quantum dots (FeO QDs) as charge storage elements. A template-assisted assembly technique is used to align FeO QDs into a close-packed, ordered matrix within the trenches that separate highly aligned SiNWs, and thus store injected charges. A Fowler-Nordheim tunneling mechanism describes both the program and erase operations. The memory prototype demonstrates promising characteristics in terms of large threshold voltage shift (~1.3 V) and long data retention time (~3 Ă— 106 s), and also allows for key components to be systematically varied. For example, varying the size of the QDs indicates that larger diameter QDs exhibit a larger memory window, suggesting the QD charging energy plays an important role in the carrier transport. The device temperature characteristics reveal an optimal window for device performance between 275K and 350K.
The flexibility of integrating the charge-trap memory devices with the SiNW logic devices offers a low-cost embedded non-volatile memory solution. A building block for a SiNW-based field-programmable gate array (FPGA) is proposed in the future work.</p
Silicon Nanowire Charge-Trap Memory Incorporating Self-Assembled Iron Oxide Quantum Dots
Charge-trap non-volatile memory devices based upon the precise integration of quantum dot storage elements with silicon nanowire field-effect transistors are described. Template-assisted assembly yields an ordered array of FeO QDs within the trenches that separate highly aligned SiNWs, and injected charges are reversibly stored via Fowler–Nordheim tunneling into the QDs. Stored charges shift the transistor threshold voltages, providing the basis for a memory device. Quantum dot size is found to strongly influence memory performance metrics
High Performance Ring Oscillators from 10-nm Wide Silicon Nanowire Field-Effect Transistors
We explore 10-nm wide Si nanowire (SiNW) field-effect transistors (FETs) for logic applications, via the fabrication
and testing of SiNW-based ring oscillators. We report on SiNW surface treatments and dielectric annealing, for
producing SiNW FETs that exhibit high performance in terms of large on/off-state current ratio (~10^8), low
drain-induced barrier lowering (~30 mV) and low subthreshold swing (~80 mV/decade). The performance of
inverter and ring-oscillator circuits fabricated from these nanowire FETs are also explored. The inverter
demonstrates the highest voltage gain (~148) reported for a SiNW-based NOT gate, and the ring oscillator
exhibits near rail-to-rail oscillation centered at 13.4 MHz. The static and dynamic characteristics of these NW
devices indicate that these SiNW-based FET circuits are excellent candidates for various high-performance
nanoelectronic applications
Engines for predictive work extraction from memoryfull quantum stochastic processes
Quantum information-processing techniques enable work extraction from a
system's inherently quantum features, in addition to the classical free energy
it contains. Meanwhile, the science of computational mechanics affords tools
for the predictive modeling of non-Markovian classical and quantum stochastic
processes. We combine tools from these two sciences to develop a technique for
predictive work extraction from non-Markovian stochastic processes with quantum
outputs. We demonstrate that this technique can extract more work than
non-predictive quantum work extraction protocols, on one hand, and predictive
work extraction without quantum information processing, on the other. We
discover a phase transition in the efficacy of knowledge for work extraction
from quantum processes, which is without classical precedent. Our work opens up
the prospect of machines that harness environmental free energy in an
essentially quantum, essentially time-varying form
Preparative isolation of paclitaxel and related taxanes from cell cultures of <i>Taxus chinensis</i> using reversed-phase flash chromatography
<div><p>In this study, paclitaxel, baccatin III, taxuyunnanine C and sinenxane C were successfully separated by reversed-phase flash chromatography on a manually packed C<sub>18</sub> column from <i>Taxus chinensis</i> cell culture extract. The crude cell culture extract was first treated with Al<sub>2</sub>O<sub>3</sub> column chromatography and then divided into two parts: fraction 1 and fraction 2. Ten milligrams of baccatin III and 19Â mg of paclitaxel were obtained from 100Â mg dried fraction 1. Fifty-two milligrams of taxuyunnanine C and 11Â mg sinenxane C were obtained from 100Â mg dried fraction 2. The purities of the four compounds were 98.02%, 98.53%, 98.93% and 98.76%, respectively. Their structures were characterised by using UV, MS and NMR. These results indicate that paclitaxel and related taxanes including baccatin III can be obtained from cell culture in a highly pure state using reversed-phase flash chromatography.</p></div
Fermentation with Tea Residues Enhances Antioxidant Activities and Polyphenol Contents in Kombucha Beverages
Kombucha is a popular beverage with various bioactivities (such as antioxidant activity), which can be attributed to its abundant bioactive compounds, especially polyphenols. Kombucha is conventionally prepared by fermentation of a sugared black tea infusion without tea residue. In this study, the effects of black tea residue and green tea residue on kombucha were studied, and its antioxidant activities, total phenolic contents, as well as concentrations of polyphenols at different fermentation stages were evaluated using ferric-reducing antioxidant power, Trolox equivalent antioxidant capacity, Folin-Ciocalteu method and high-performance liquid chromatography with a photodiode array detector. The results showed that fermentation with tea residue could markedly increase antioxidant activities (maximum 3.25 times) as well as polyphenolic concentrations (5.68 times) of kombucha. In addition, green tea residue showed a stronger effect than black tea residue. Overall, it is interesting to find that fermentation with tea residues could be a better strategy to produce polyphenol-rich kombucha beverages
Possible Effects and Mechanisms of Dietary Natural Products and Nutrients on Depression and Anxiety: A Narrative Review
Depression and anxiety are severe public health problems and have attracted more and more attention from researchers of food science and nutrition. Dietary natural products and nutrients, such as fish, coffee, tea, n-3 PUFA, lycopene, and dietary fiber, could play a vital role in the prevention and management of these diseases. The potential mechanisms of action mainly include inhibiting inflammation, ameliorating oxidative stress, modulating the microbiota–gut–brain axis, suppressing hypothalamic–pituitary–adrenal axis hyperactivity, and regulating the levels of monoamine neurotransmitters. In this narrative review, we summarize the most recent advancements regarding the effects of dietary natural products and nutrients on depression and anxiety, and their underlying mechanisms are discussed. We hope that this paper can provide a better understanding of the anti-depressive and anxiolytic action of dietary natural products, and that it is also helpful for developing dietary natural products for functional food, dietary supplements, or auxiliary agents for the prevention and management of these diseases